writhe -
To make continual twisting, squirming movements or contortions of the body
The soccer player writhed in pain on the ground after spraining his ankle.
noun
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anguish -
Severe mental or physical pain or suffering
With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.
noun
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pang -
A sudden sharp pain or painful emotion
The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.
adjective
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impoverished -
Very poor.
We can hardly imagine how impoverished the average person was during the Middle Ages.
noun
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cramps -
A painful, involuntary contraction of muscles
When Sharon got cramps in her stomach after eating the fish, she suspected that it may have been spoiled.
adjective
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agonizing -
Something that causes great physical or mental pain.
After she took the final exam, it was agonizing to her that for a whole week she wouldn't find out the results.
adjective
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tragic -
Something very sad often involving suffering.
The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.
verb
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flinch -
To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain
Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.
verb
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bruise -
To hurt someone emotionally or physically, leaving a lasting feeling of pain or vulnerability.
The teacher's harsh words bruised his self-esteem.
verb
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wince -
To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress
Tiger winced as he realized he had hit the ball too far beyond the hole.
adjective
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afflicted -
Suffering from a serious problem, illness, or pain, be it mental or physical.
Many people are afflicted with anxiety in high-pressure situations.
noun
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throes -
Intense or violent pain and struggle, especially accompanying birth, death, or great change
Samantha experienced agonizing pain during the throes of childbirth.