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noun

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ingratitude - A lack of proper appreciation or thanks for something that was given or done.

She was shocked at her son's ingratitude that after raising him for 20 years, when he moved out he hardly ever called.

verb

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irritate - To make someone angry, or annoyed; or to make apart of your body sore or painful.

After the mother spent hours peparing the Friday night meal, she was irritated when the whole family ate quickly and left without thanking her or even saying anything in appreciation.

verb

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neglect - To fail to care of something or someone properly.

During a mass emergency, it's important for the emergency room staff to remember not to neglect their need to eat and sleep.

adjective

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indifferent - Not showing or feeling interest or concern about something.

In the 1700's, the upper classes were generally indifferent to the suffering and hunger of the poor.