berserk -
To behave in a wild and uncontrolled way as a result of something unexpected happening.
When Anne found out that she had lost all her money as a result of stock fraud, she went berserk, running around the house, screaming and breaking dishes.
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hysterical -
Having uncontrolled extreme emotion
When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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deranged -
Behaving in an uncontrolled or dangerous way because of mental illness
Charles Manson led a group of followers who became mentally deranged as a result of taking too many psychedelic drugs
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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lunatic -
A person who is crazy
Martha was a defensive driver, to be safer with regards to a possible lunatic behind the wheel of another car.
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maniac -
Someone who is mentally ill tending towards violent and dangerous behavior.
The film’s villain was portrayed as a ruthless maniac with no regard for human life.
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delirious -
In a disturbed state of mind, often due to illness or fever, leading to confusion and hallucinations.
After three sleepless nights, he was delirious and barely able to speak clearly.
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lunacy -
Stupid or crazy ideas or behavior that is likely to have bad results
When Edwin Hubble suggested in 1922 that most of the little dots in the sky are entire galaxies, most scientists thought that the idea was sheer lunacy.
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.
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cantankerous -
Bad-tempered, argumentative, and uncooperative
The constant arguing of the cantankerous couple living above Ann always kept her up at night.
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wacky -
Something that is strange and different to the point of amusement.
George’s grandmother was well known and loved for her wacky taste in shoes.